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Vitamind
Vitamin D is one of the essential nutrients for the human body. Vitamin D is essentially synthesized from sunlight. However dietary source can also add to vitamin D levels. The prevalence of polar to equatorial countries gradient in autoimmune diseases has lead to emergence of hypothesis that the vitamin D deficiency results in development of autoimmune disorder. However such an hypothesis ignore the dietary source of vitamin D which is severely limited in the equatorial countries.
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The study of Vitamin D levels in various autoimmune diseases by considering both the sunlight exposure and dietary intake can resolve the role of vitamin D in development of several autoimmune disorder. The ability to alter the vitamin D levels in blood by dietary means is not clear. As a result Vitamin D is currently used only as prophylaxis.
Hygiene Hypothesis
Are we a parasitic host to bacteria?
For more than 100 years we have taught that being hygienic is an healthy state. However, The increase in prevalence of autoimmune disorder in past 50 years questioned the conventional wisdom. With the decline in communicable disease, a concurrent increase in autoimmune disorder lead to the suggestion that the bacteria present in the human body are essential for health state and work in symbiosis.
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However, this lead to inference that human body is susceptible to various autoimmune disease in sterile state. Studying the hygiene hypothesis will enable us to manipulate the bacteria thus provide a way to treat autoimmune diseases.
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